A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines
Figure 3
AZA inhibits protein synthesis in KG-1a and THP-1 cells.
Cells were treated daily with AZA or DAC (0–5 µM) for 24 or 48 hours prior to metabolic labeling with 35S-methionine and 35S-cysteine. Protein synthesis was quantified as described previously. AZA = azacitidine; DAC = decitabine.