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A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines

Figure 1

AZA and DAC differentially affect cell viability in AML cell lines.

Cell viability of AML cell lines, KG-1a, THP-1, OCI-AML3, and HL-60, was assessed after 72 hours of treatment with AZA (•) or DAC (□) (0–50 µM) using the CellTiter-Glo assay. Standard deviation was determined from 2 or 3 independent experiments, including triplicate wells per experiment. AML = acute myeloid leukemia; AZA = azacitidine; DAC = decitabine.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0009001.g001