Muscle-Specific Adaptations, Impaired Oxidative Capacity and Maintenance of Contractile Function Characterize Diet-Induced Obese Mouse Skeletal Muscle
Figure 5
Oxidative enzyme alterations are muscle specific.
Citrate synthase (CS) activity is unaltered in both (A) TA and (C) soleus muscle between control (CON) and high fat diet (HFD). Short chain 3-β-hydroxyacyl coenzyme-A dehydrogenase (SCHAD) activity is unaltered in (B) TA muscle, though (D) soleus muscle from HFD mice exhibits SCHAD activity 136% of CON. Significance is represented by * vs. CON, p<0.005.