Proteomic Interrogation of Androgen Action in Prostate Cancer Cells Reveals Roles of Aminoacyl tRNA Synthetases
Figure 4
Molecular concepts of androgen up-regulated proteins from two mass spectrometry platforms.
Network view of molecular concepts or sets of biologically related genes enriched in androgen up-regulated protein set obtained through Molecular Concepts Mapping (MCM) analysis. Each node represents a biological concept; the node size is proportional to the number of genes in each concept. Each edge represents a statistically significant enrichment. P-value of each concept and the MCM number of the concept are given in brackets. The most enriched concept is indicated by a thick edge. Red colored edges indicate enrichment of known prostate cancer-specific and androgen-regulated concepts. Interconnected aminoacyl tRNA synthetase concepts are indicated in blue edges at the bottom of the network.