Sequential Metabolism of 7-Dehydrocholesterol to Steroidal 5,7-Dienes in Adrenal Glands and Its Biological Implication in the Skin
Figure 3
Metabolism of 7-DHC by adrenal glands of different mammalian species.
Finely cut fragments of rat (A), rabbit (B), dog (C) and pig (D) adrenals were incubated in the presence (blue) or absence (green) of 7DHC (S). Boiled adrenal fragments served as an additional negative control for the rat (red). The three major products common to all animals studied are numbered 1 to 3 on the chromatograms. Product 3 had an identical retention time, mass, and UV spectra to 7DHP standard.