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Imaging Mass Spectrometry Technology and Application on Ganglioside Study; Visualization of Age-Dependent Accumulation of C20-Ganglioside Molecular Species in the Mouse Hippocampus

Figure 1

Structure of C18-LCB containing GM1a.

Gangliosides comprise a large family; their oligosaccharides structures differ in the glycosidic linkage position, sugar configuration, and the contents of neutral sugars and sialic- acid content. The ceramide moiety of gangliosides, it also has some variation varies with respect to the type of long -chain base (LCB) (sphingosine- base) and fatty acid moiety.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0003232.g001