Population Substructure and Control Selection in Genome-Wide Association Studies
Figure 2
Samples represented by their first two principal components.
Principal components (PC, the 1st along the horizontal direction, the 2nd along the vertical direction)) were obtained by applying the PCA on the joint sample of PLCO prostate cancer and NHS breast cancer studies. A) First two PCs for subjects from the PLCO prostate cancer study. B) First two PCs for subjects from the NHS breast cancer study.