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Phage-Antibiotic Synergy (PAS): β-Lactam and Quinolone Antibiotics Stimulate Virulent Phage Growth

Figure 5

The PAS effect of phage T4 on various E. coli SOS and filamentation mutant strains.

T4 was grown on E. coli sulA-inactivated and lexA non-inducible mutant strains (defective SOS systems), as well as an ftsZ-inactivated mutant strain (non-antibiotic induced filamentation), in the presence of disks of cefotaxime (CTX). Isogenic wild-type strains (wt) are also included and representative plaques demonstrating the PAS effect are indicated by red arrows. All plates were photographed at identical magnifications.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0000799.g005