Selection against Spurious Promoter Motifs Correlates with Translational Efficiency across Bacteria
Figure 5
NSD of −10 motif counts in nonfunctional DNA correlate negatively with the number of tRNA genes in the genome.
NSD values are defined as in the text and Figure 4. The red line represents −2 SD from the mean expected value of −10 motif counts in the nonfunctional DNA of the corresponding genome. The green line indicates the average number of tRNA genes in the genomes analyzed (55). The color-coding distinguishes species according to their maximal growth rate (see Table 1); no growth rate estimate was available for Corynebacterium glutamicum (not colored). Black dotted line: regression including all analyzed genomes (r = 0.38 and p<0.02). Black solid line: regression for the subset of genomes with NSD<−2 in nonfunctional DNA (r = 0.63 and p<0.001).