Network toxicology, molecular docking and molecular dynamics simulations for bisphenol A neurotoxicity in depression pathogenesis

Jinlian Zhang; Yuanhao Ma; Miguo Lu; Xiaohuan Jiang; Qingmi Zhong; Yan Zhang; Yan Xiong; Qiliang Wu; Lina Chen; Ruikang Pang

doi:10.1371/journal.pone.0359940

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Open Access

Peer-reviewed

Research Article

Network toxicology, molecular docking and molecular dynamics simulations for bisphenol A neurotoxicity in depression pathogenesis

Jinlian Zhang ,

Contributed equally to this work with: Jinlian Zhang, Yuanhao Ma

Roles Conceptualization, Data curation, Writing – original draft

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Yuanhao Ma ,

Contributed equally to this work with: Jinlian Zhang, Yuanhao Ma

Roles Data curation, Software, Visualization, Writing – original draft

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Miguo Lu,

Roles Software, Visualization

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Xiaohuan Jiang,

Roles Data curation

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Qingmi Zhong,

Roles Data curation

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Yan Zhang,

Roles Data curation

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Yan Xiong,

Roles Supervision

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Qiliang Wu,

Roles Software

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Lina Chen,

Roles Project administration, Visualization

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China
⨯
Ruikang Pang

Roles Project administration, Resources, Supervision, Writing – review & editing

* E-mail: 20222110132@stu.gzucm.edu.cn

Affiliation The Eighth People’s Hospital of Nanning, Nanning, Guangxi, China

https://orcid.org/0009-0004-4859-4343

⨯

Network toxicology, molecular docking and molecular dynamics simulations for bisphenol A neurotoxicity in depression pathogenesis

Jinlian Zhang,
Yuanhao Ma,
Miguo Lu,
Xiaohuan Jiang,
Qingmi Zhong,
Yan Zhang,
Yan Xiong,
Qiliang Wu,
Lina Chen,
Ruikang Pang

Published: October 5, 2026
https://doi.org/10.1371/journal.pone.0359940

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