Age-related molecular and functional remodeling of the choroid plexus in the gray mouse lemur

Florent Amiot; Antxon Etchebest; Bijou Andriambelo; Joannie St-Germain; Mariano Avino; Mélanie Plourde; Benoit Laurent; Fabien Pifferi

doi:10.1371/journal.pone.0357233

Loading metrics

Open Access

Peer-reviewed

Research Article

Age-related molecular and functional remodeling of the choroid plexus in the gray mouse lemur

Florent Amiot ,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

¶☯ These authors share first authorship

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, UMR CNRS MNHN 7179 MECADEV - Mécanismes Adaptatifs et Évolution, Brunoy, France

https://orcid.org/0009-0006-1992-3536

⨯
Antxon Etchebest ,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

¶☯ These authors share first authorship

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯
Bijou Andriambelo,

Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯
Joannie St-Germain,

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯
Mariano Avino,

Roles Formal analysis, Investigation, Software, Visualization, Writing – review & editing

Affiliation Bio-informatic platform, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada

https://orcid.org/0000-0002-6796-2453

⨯
Mélanie Plourde,

Roles Funding acquisition, Resources, Supervision, Writing – review & editing

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, Institut sur la Nutrition et les Aliments Fonctionnels, Université Laval, Québec City, Québec, Canada
⨯
Benoit Laurent ,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: benoit.laurent@usherbrooke.ca (BL), fabien.pifferi@mnhn.fr (FP)

Affiliations Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l’Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada

https://orcid.org/0000-0002-4032-3213

⨯
Fabien Pifferi

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: benoit.laurent@usherbrooke.ca (BL), fabien.pifferi@mnhn.fr (FP)

Affiliation UMR CNRS MNHN 7179 MECADEV - Mécanismes Adaptatifs et Évolution, Brunoy, France
⨯

Age-related molecular and functional remodeling of the choroid plexus in the gray mouse lemur

Florent Amiot,
Antxon Etchebest,
Bijou Andriambelo,
Joannie St-Germain,
Mariano Avino,
Mélanie Plourde,
Benoit Laurent,
Fabien Pifferi

Published: August 31, 2026
https://doi.org/10.1371/journal.pone.0357233

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lemurs
Is the Subject Area "Lemurs" applicable to this article?

Thanks for your feedback.
Aging
Is the Subject Area "Aging" applicable to this article?

Thanks for your feedback.
Cerebrospinal fluid
Is the Subject Area "Cerebrospinal fluid" applicable to this article?

Thanks for your feedback.
Age groups
Is the Subject Area "Age groups" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Mice
Is the Subject Area "Mice" applicable to this article?

Thanks for your feedback.
Animal performance
Is the Subject Area "Animal performance" applicable to this article?

Thanks for your feedback.
Primates
Is the Subject Area "Primates" applicable to this article?

Thanks for your feedback.