4D-DIA proteomics reveals distinct proteolytic landscapes induced by mechanical stress, Agrobacterium, and a viral capsid precursor

You Tang; Xiaoping Qiu; Xinli Ye; Xiaorui Ma; Yilin Mao; Qiwei Yang; Yike Chen; Yiming Sun; Lijun Zhu

doi:10.1371/journal.pone.0356905

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Open Access

Peer-reviewed

Research Article

4D-DIA proteomics reveals distinct proteolytic landscapes induced by mechanical stress, Agrobacterium, and a viral capsid precursor

You Tang ,

Contributed equally to this work with: You Tang, Xiaoping Qiu

Roles Data curation, Formal analysis, Investigation, Software, Visualization, Writing – original draft

Affiliation Chongqing Key Laboratory of Scientific Utilization of Tobacco Resources, Chongqing, China

https://orcid.org/0009-0004-0990-5145

⨯
Xiaoping Qiu ,

Contributed equally to this work with: You Tang, Xiaoping Qiu

Roles Data curation, Investigation, Validation, Writing – original draft, Writing – review & editing

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Xinli Ye,

Roles Investigation, Validation

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Xiaorui Ma,

Roles Investigation, Validation

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Yilin Mao,

Roles Investigation

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Qiwei Yang,

Roles Investigation

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Yike Chen,

Roles Investigation

Affiliation School of Life Science, Southwest University, Chongqing, China
⨯
Yiming Sun ,

Roles Funding acquisition, Project administration, Resources, Writing – review & editing

* E-mail: s8355@swu.edu.cn (YS); zhulj7802@163.com (LZ)

Affiliation School of Life Science, Southwest University, Chongqing, China

https://orcid.org/0000-0003-2299-8505

⨯
Lijun Zhu

Roles Conceptualization, Funding acquisition, Supervision

* E-mail: s8355@swu.edu.cn (YS); zhulj7802@163.com (LZ)

Affiliation Chongqing Key Laboratory of Scientific Utilization of Tobacco Resources, Chongqing, China
⨯

4D-DIA proteomics reveals distinct proteolytic landscapes induced by mechanical stress, Agrobacterium, and a viral capsid precursor

You Tang,
Xiaoping Qiu,
Xinli Ye,
Xiaorui Ma,
Yilin Mao,
Qiwei Yang,
Yike Chen,
Yiming Sun,
Lijun Zhu

Published: September 11, 2026
https://doi.org/10.1371/journal.pone.0356905

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Proteases
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