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Open Access

Peer-reviewed

Research Article

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu,

Roles Formal analysis, Methodology, Software, Validation, Writing – original draft

Affiliation Department of Radiology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
⨯
Yingzhuo Li,

Roles Formal analysis, Visualization, Writing – original draft

Affiliation Department of Radiology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
⨯
Bosheng Luo,

Roles Conceptualization, Investigation, Writing – original draft

Affiliation Department of Radiology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
⨯
Yang Wang,

Roles Data curation, Supervision, Writing – original draft

Affiliation Department of Radiology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
⨯
Chunjuan Xia,

Roles Investigation, Writing – review & editing

Affiliation Department of Ultrasound, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
⨯
Jiaping Wang

Roles Funding acquisition, Writing – review & editing

* E-mail: jiapingwang12@163.com

Affiliation Department of Radiology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

https://orcid.org/0000-0002-4042-7346

⨯

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu,
Yingzhuo Li,
Bosheng Luo,
Yang Wang,
Chunjuan Xia,
Jiaping Wang

x

Published: August 20, 2026
https://doi.org/10.1371/journal.pone.0356691

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Parkinson disease
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Transcriptome analysis
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Metaanalysis
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Kidneys
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Microarrays
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Bone marrow cells
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Immune receptor signaling
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