L-Phenylalanine restriction enhances L-boronophenylalanine uptake and improves boron neutron capture therapy efficacy in tumor cell lines

• Yuki Tamari ,

  Contributed equally to this work with: Yuki Tamari, Rie Saba

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yuki.tamari@fujita-hu.ac.jp (YT); rsaba@koto.kpu-m.ac.jp (RS)

  Affiliations Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan, Department of Medical Information Engineering, Research Promotion Unit, School of Medical Science, Fujita Health University, Aichi, Japan

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• Rie Saba ,

  Contributed equally to this work with: Yuki Tamari, Rie Saba

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yuki.tamari@fujita-hu.ac.jp (YT); rsaba@koto.kpu-m.ac.jp (RS)

  Affiliations Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, Division of Anatomy and Developmental Biology, Department of Anatomy, Kyoto Prefectural University of Medicine, Kyoto, Japan

  https://orcid.org/0009-0008-1813-840X

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• Takushi Takata,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan

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• Hiroyuki Kimura,

  Roles Resources, Writing – review & editing

  Current address: Agency of Health, Safety and Environment, Kyoto University, Kyoto, Japan

  Affiliation Division of Probe Chemistry for Disease Analysis, Research Center for Experimental Modeling of Human Disease, Kanazawa University, Ishikawa, Japan

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• Mao Takita,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Shimadzu Techno-Research Inc, Kyoto, Japan

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• Kenta Yashiro,

  Roles Resources, Writing – review & editing

  Affiliation Division of Anatomy and Developmental Biology, Department of Anatomy, Kyoto Prefectural University of Medicine, Kyoto, Japan

  https://orcid.org/0000-0002-2816-5662

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• Minoru Suzuki,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliation Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan

  https://orcid.org/0000-0002-5421-9417

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• Hideya Yamazaki,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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• Kei Yamada

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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