Central and peripheral plasticity after chemical unilateral labyrinthectomy: Glial responses, calyces dynamics, and behavioral consequences

Jessica Trico; Isabelle Watabe; Vinay Parameshwarappa; Agnes Lapotre; Louis Godaert; Alain Tonetto; Christian Chabbert; Andreas Zwergal; Brahim Tighilet

doi:10.1371/journal.pone.0355839

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Open Access

Peer-reviewed

Research Article

Central and peripheral plasticity after chemical unilateral labyrinthectomy: Glial responses, calyces dynamics, and behavioral consequences

Jessica Trico,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France

https://orcid.org/0000-0002-1300-9499

⨯
Isabelle Watabe,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France

https://orcid.org/0000-0003-4881-8592

⨯
Vinay Parameshwarappa,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France
⨯
Agnes Lapotre,

Roles Investigation, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France
⨯
Louis Godaert,

Roles Investigation, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, Centrale Med, FSCM (UAR1739), Plateforme de Recherche Analytique Technologique et Imagerie (PRATIM), Marseille, France
⨯
Alain Tonetto,

Roles Investigation, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, Centrale Med, FSCM (UAR1739), Plateforme de Recherche Analytique Technologique et Imagerie (PRATIM), Marseille, France
⨯
Christian Chabbert,

Roles Investigation, Writing – review & editing

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France
⨯
Andreas Zwergal,

Roles Supervision, Validation, Visualization, Writing – review & editing

Affiliations Department of Neurology, LMU University Hospital, LMU Medizin, LMU Munich, Munich, Germany, German Center for Vertigo and Balance Disorders (DSGZ), LMU University Hospital, LMU Medizin, LMU Munich, Munich, Germany
⨯
Brahim Tighilet

Roles Conceptualization, Investigation, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: brahim.tighilet@univ-amu.fr

Affiliation Aix Marseille Univ, CNRS, CRPN (Centre de Recherche en Psychologie et Neurosciences UMR 7077), Marseille, France
⨯

Central and peripheral plasticity after chemical unilateral labyrinthectomy: Glial responses, calyces dynamics, and behavioral consequences

Jessica Trico,
Isabelle Watabe,
Vinay Parameshwarappa,
Agnes Lapotre,
Louis Godaert,
Alain Tonetto,
Christian Chabbert,
Andreas Zwergal,
Brahim Tighilet

Published: September 1, 2026
https://doi.org/10.1371/journal.pone.0355839

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