Vitamin B12 combined with methylene blue alleviates experimental septic shock and is associated with modulation of KCNMB1 and the cGMP-PRKG pathway

• Keji Shan ,

  Contributed equally to this work with: Keji Shan, Jinling Zhao

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  * E-mail: skjicu@163.com

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

  https://orcid.org/0009-0002-3052-1387

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• Jinling Zhao ,

  Contributed equally to this work with: Keji Shan, Jinling Zhao

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

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• Kun Tang,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

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• Yuying Lei,

  Roles Data curation, Validation

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

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• Fukang Mao

  Roles Data curation, Validation

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

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