Identification and risk-factor analysis for individuals at high risk for keratoconus via machine learning and logistic regression

Kaiyue Du; Rongmei Peng; Yueguo Chen; Bowei Yuan; Wei Chen; Liang Han; Gege Xiao; Yi Qu; Jing Hong

doi:10.1371/journal.pone.0354924

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Open Access

Peer-reviewed

Research Article

Identification and risk-factor analysis for individuals at high risk for keratoconus via machine learning and logistic regression

Kaiyue Du,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Rongmei Peng,

Roles Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Yueguo Chen,

Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Bowei Yuan,

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Wei Chen,

Roles Conceptualization, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliation Institute of Automation, Chinese Academy of Sciences, Beijing, China
⨯
Liang Han,

Roles Data curation, Investigation, Resources, Supervision, Writing – review & editing

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Gege Xiao,

Roles Data curation, Formal analysis, Resources, Writing – review & editing

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Yi Qu,

Roles Data curation, Investigation, Resources

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
⨯
Jing Hong

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: hongjing196401@163.com

Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China

https://orcid.org/0000-0002-8079-2073

⨯

Identification and risk-factor analysis for individuals at high risk for keratoconus via machine learning and logistic regression

Kaiyue Du,
Rongmei Peng,
Yueguo Chen,
Bowei Yuan,
Wei Chen,
Liang Han,
Gege Xiao,
Yi Qu,
Jing Hong

Published: August 25, 2026
https://doi.org/10.1371/journal.pone.0354924

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