Drug sensitivity prediction across cancer types using graph isomorphism networks and biological pathway features: A dual-branch deep learning approach

• Shuang Li,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China, Zhongyuan Scholars Workstation of Henan, Luoyang Polytechnic, Luoyang, Henan, China, Henan Engineering Research Center, Key Immunological Biomaterials, Luoyang Polytechnic, Luoyang, Henan, China, Luoyang Key Laboratory of POCT Diagnosis Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Quanzhong Yang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Feifei Shen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Wei Chen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Shuya Zhang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Xinyi Dong,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China

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• Weikai Zhang

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: weikaizhangreas@hotmail.com

  Affiliations Institute of Medical Technology, Luoyang Polytechnic, Luoyang, Henan, China, Zhongyuan Scholars Workstation of Henan, Luoyang Polytechnic, Luoyang, Henan, China, Henan Engineering Research Center, Key Immunological Biomaterials, Luoyang Polytechnic, Luoyang, Henan, China, Luoyang Key Laboratory of POCT Diagnosis Technology, Luoyang Polytechnic, Luoyang, Henan, China

  https://orcid.org/0009-0009-3336-4509

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