IL5 rs2069812 and IL13 rs1800925 Genetic variants as key determinants of clinically relevant asthma phenotypes

Pattara Kanoksing; Apichaya Puangpetch; Theerasuk Kawamatawong; Thatchathum Kuttiyod; Kantapat Simmalee; Roger Frutos; Putthapoom Lumjiaktase

doi:10.1371/journal.pone.0354597

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Open Access

Peer-reviewed

Research Article

IL5 rs2069812 and IL13 rs1800925 Genetic variants as key determinants of clinically relevant asthma phenotypes

Pattara Kanoksing,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Apichaya Puangpetch,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Supervision

Affiliation Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Theerasuk Kawamatawong,

Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Thatchathum Kuttiyod,

Roles Formal analysis, Software

Affiliation Ratchasuda Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Kantapat Simmalee,

Roles Conceptualization, Formal analysis, Resources, Software

Affiliation Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Roger Frutos,

Roles Supervision, Writing – review & editing

Affiliations Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, Cirad, Intertryp U.M.R.17, Montpellier, France, Department of Health, Faculty of Vocational Studies, Universitas Airlangga, Surabaya, Indonesia
⨯
Putthapoom Lumjiaktase

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: putthapoom@gmail.com

Affiliation Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

https://orcid.org/0000-0001-8013-6204

⨯

IL5 rs2069812 and IL13 rs1800925 Genetic variants as key determinants of clinically relevant asthma phenotypes

Pattara Kanoksing,
Apichaya Puangpetch,
Theerasuk Kawamatawong,
Thatchathum Kuttiyod,
Kantapat Simmalee,
Roger Frutos,
Putthapoom Lumjiaktase

Published: July 24, 2026
https://doi.org/10.1371/journal.pone.0354597

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Asthma
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Variant genotypes
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Alleles
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Inflammation
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Cytokines
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Eosinophils
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Blood
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Single nucleotide polymorphisms
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