Efficacy comparison of concurrent chemoradiotherapy alone versus concurrent chemoradiotherapy plus adjuvant chemotherapy in stage III Locally Advanced Cervical Cancer: A single-center, retrospective observational cohort study

Haizhou Yang; Yaxian Tan; Yajun Pang; Xiaowen Chen; Guoqiang Chen; Caixia Liang; Manyu Chen; Qiulong Liu; Zhihao Li; Jierong Xie; Zhennan Wang; Sihai Liao; Yufang Zuo

doi:10.1371/journal.pone.0354207

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Open Access

Peer-reviewed

Research Article

Efficacy comparison of concurrent chemoradiotherapy alone versus concurrent chemoradiotherapy plus adjuvant chemotherapy in stage III Locally Advanced Cervical Cancer: A single-center, retrospective observational cohort study

Haizhou Yang ,

Contributed equally to this work with: Haizhou Yang, Yaxian Tan

Roles Formal analysis, Software, Writing – original draft

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China

https://orcid.org/0000-0002-4105-9995

⨯
Yaxian Tan ,

Contributed equally to this work with: Haizhou Yang, Yaxian Tan

Roles Investigation

Affiliations Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China, Department of Oncology, Zizhong County Traditional Chinese Medicine Hospital, Neijiang, Sichuan Province, China
⨯
Yajun Pang,

Roles Data curation

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Xiaowen Chen,

Roles Visualization

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Guoqiang Chen,

Roles Visualization

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Caixia Liang,

Roles Conceptualization

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Manyu Chen,

Roles Formal analysis, Investigation

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Qiulong Liu,

Roles Data curation

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Zhihao Li,

Roles Data curation

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Jierong Xie,

Roles Resources, Supervision

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Zhennan Wang,

Roles Supervision

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Sihai Liao ,

Roles Investigation, Resources, Validation

* E-mail: yufangzuo0102@163.com (YZ); liaosihai163@163.com (SL)

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯
Yufang Zuo

Roles Resources, Writing – review & editing, Validation

* E-mail: yufangzuo0102@163.com (YZ); liaosihai163@163.com (SL)

Affiliation Department of Gynecologic and Genitourinary Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
⨯

Efficacy comparison of concurrent chemoradiotherapy alone versus concurrent chemoradiotherapy plus adjuvant chemotherapy in stage III Locally Advanced Cervical Cancer: A single-center, retrospective observational cohort study

Haizhou Yang,
Yaxian Tan,
Yajun Pang,
Xiaowen Chen,
Guoqiang Chen,
Caixia Liang,
Manyu Chen,
Qiulong Liu,
Zhihao Li,
Jierong Xie

Published: August 10, 2026
https://doi.org/10.1371/journal.pone.0354207

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