Bo-Net: Deep learning-based model for automatic bone stromal cell segmentation of fluorescence microscopy images

• Giorgio Allegri ,

  Contributed equally to this work with: Giorgio Allegri, Luca Pavirani, Sergio Barrios

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶† Deceased.

  Affiliations Department of Electronics, Information and Bioengineering, Polytechnic University of Milan, Milan, Italy, Center for Precision Surgery, Houston Methodist Research Institute, Houston, Texas, United States of America

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• Luca Pavirani ,

  Contributed equally to this work with: Giorgio Allegri, Luca Pavirani, Sergio Barrios

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Electronics, Information and Bioengineering, Polytechnic University of Milan, Milan, Italy, Center for Precision Surgery, Houston Methodist Research Institute, Houston, Texas, United States of America

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• Sergio Barrios ,

  Contributed equally to this work with: Giorgio Allegri, Luca Pavirani, Sergio Barrios

  Roles Data curation, Writing – review & editing

  Affiliations David H. Koch Center for Applied Research of Genitourinary Cancers and Genitourinary Medical Oncology Department, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Rice University, Dept. of Bioengineering, Houston, Texas, United States of America

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• Sofia Rosy Caterina Sorice,

  Roles Data curation, Formal analysis, Methodology

  Affiliation David H. Koch Center for Applied Research of Genitourinary Cancers and Genitourinary Medical Oncology Department, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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• Giulia Alessandrelli,

  Roles Conceptualization, Data curation, Formal analysis, Methodology

  Affiliation Department of Electronics, Information and Bioengineering, Polytechnic University of Milan, Milan, Italy

  https://orcid.org/0000-0003-4924-1094

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• Luca Marsilio,

  Roles Data curation, Formal analysis

  Affiliations Department of Electronics, Information and Bioengineering, Polytechnic University of Milan, Milan, Italy, Center for Precision Surgery, Houston Methodist Research Institute, Houston, Texas, United States of America

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• Antonios Mikos,

  Roles Conceptualization, Investigation, Resources

  Affiliation Rice University, Dept. of Bioengineering, Houston, Texas, United States of America

  https://orcid.org/0000-0002-0709-990X

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• Pietro Cerveri,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Electronics, Information and Bioengineering, Polytechnic University of Milan, Milan, Italy

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• Stefano Casarin ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: SCasarin@houstonmethodist.org (SC); EDondossola@mdanderson.org (ED)

  ¶‡ SC and ED authors also contributed equally to this work.

  Affiliations Center for Precision Surgery, Houston Methodist Research Institute, Houston, Texas, United States of America, Department of Surgery, Houston Methodist Hospital, Houston, Texas, United States of America, LaSIE, UMR CNRS, La Rochelle Université, La Rochelle, France

  https://orcid.org/0000-0002-7416-2366

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• Eleonora Dondossola

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing, Conceptualization

  * E-mail: SCasarin@houstonmethodist.org (SC); EDondossola@mdanderson.org (ED)

  ¶‡ SC and ED authors also contributed equally to this work.

  Affiliations David H. Koch Center for Applied Research of Genitourinary Cancers and Genitourinary Medical Oncology Department, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Rice University, Dept. of Bioengineering, Houston, Texas, United States of America

  https://orcid.org/0000-0001-6916-5418

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