Characterization of a novel lncRNA RP3-340N1.2 and its association with a miR-4650-5p/SHC1-related regulatory network in lung adenocarcinoma

Fang Chen; Yan Yan; Wenting Yang; Zhilin Li; Daying Wang; Jianqiao Huang; Chaozhou Wan; Tingting An; Li Tong; Maoxia Ran; Yaqiong Dong; Yunfen Chen

doi:10.1371/journal.pone.0353744

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Open Access

Peer-reviewed

Research Article

Characterization of a novel lncRNA RP3-340N1.2 and its association with a miR-4650-5p/SHC1-related regulatory network in lung adenocarcinoma

Fang Chen ,

Contributed equally to this work with: Fang Chen, Yan Yan

Roles Conceptualization, Data curation, Investigation, Software, Writing – original draft

Affiliations Guizhou Medical University, Guiyang, Guizhou, P.R. China, Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China

https://orcid.org/0009-0001-6528-5583

⨯
Yan Yan ,

Contributed equally to this work with: Fang Chen, Yan Yan

Roles Investigation, Writing – original draft

Affiliation Guiqian International Hospital, Guiyang, Guizhou, P.R. China
⨯
Wenting Yang,

Roles Investigation, Visualization, Writing – review & editing

Affiliation Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, P.R. China
⨯
Zhilin Li,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Daying Wang,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Jianqiao Huang,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Chaozhou Wan,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Tingting An,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Li Tong,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Maoxia Ran,

Roles Investigation

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯
Yaqiong Dong ,

Roles Project administration, Software, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: 13398746123@189.cn (YD); 1606814152@qq.com (YC)

Affiliation Guizhou Medical University, Guiyang, Guizhou, P.R. China
⨯
Yunfen Chen

Roles Methodology, Project administration, Writing – review & editing

* E-mail: 13398746123@189.cn (YD); 1606814152@qq.com (YC)

Affiliation Guizhou Provincial Staff Hospital, Guiyang, Guizhou, P.R. China
⨯

Characterization of a novel lncRNA RP3-340N1.2 and its association with a miR-4650-5p/SHC1-related regulatory network in lung adenocarcinoma

Fang Chen,
Yan Yan,
Wenting Yang,
Zhilin Li,
Daying Wang,
Jianqiao Huang,
Chaozhou Wan,
Tingting An,
Li Tong,
Maoxia Ran

Published: July 16, 2026
https://doi.org/10.1371/journal.pone.0353744

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Long non-coding RNA
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