Sivelestat sodium alleviates sepsis-associated acute lung injury by inhibiting ferroptosis via the Nrf2/SLC7A11/GPX4 axis

• Ying Wang ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Writing – original draft

  ¶☯ These authors contributed equally to this work and should be considered co-first authors.

  Affiliation Department of Critical Care Medicine, Nantong First People’s Hospital, Nantong, Jiangsu, China

  https://orcid.org/0009-0002-4274-7412

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• Xiaoling Xia ,

  Roles Conceptualization, Methodology, Writing – original draft

  ¶☯ These authors contributed equally to this work and should be considered co-first authors.

  Affiliation Department of Respiratory and Critical Care Medicine, Hai’an Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, China

  ⨯
• Yan Lu,

  Roles Formal analysis, Investigation, Project administration, Resources, Writing – original draft

  Affiliation Department of Obstetrical, Nantong First People’s Hospital, Nantong, Jiangsu, China

  ⨯
• ChengLiang Zhang,

  Roles Formal analysis, Methodology

  Affiliation Department of Critical Care Medicine, Nantong First People’s Hospital, Nantong, Jiangsu, China

  ⨯
• Yaqing Zhou ,

  Roles Conceptualization, Formal analysis, Methodology, Software, Writing – original draft

  * E-mail: fanjj01_nj@163.com (JF); sysxzs@163.com (YZ)

  ¶‡ These authors contributed equally to this work and should be considered co-corresponding author.

  Affiliation Department of Critical Care Medicine, Affiliated Hai’an Hospital of Nantong University, Hai’an County, Nantong, Jiangsu, China

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• Jingjing Fan

  Roles Data curation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: fanjj01_nj@163.com (JF); sysxzs@163.com (YZ)

  ¶‡ These authors contributed equally to this work and should be considered co-corresponding author.

  Affiliation Journal Academic Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China

  https://orcid.org/0009-0008-8313-3445

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