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Open Access

Peer-reviewed

Research Article

TBX20 promotes doxorubicin resistance in breast cancer cells through enhanced ABCC1 expression and inhibition of mitophagy

Shuai Nie,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Physician of general surgery, Hunan Aerospace Hospital Affiliated to Hunan Normal University, Changsha, China
⨯
Dejian Liu,

Roles Data curation, Investigation

Affiliation Physician of general surgery, Hunan Aerospace Hospital Affiliated to Hunan Normal University, Changsha, China
⨯
Jun Hu,

Roles Data curation, Investigation

Affiliation Physician of general surgery, Hunan Aerospace Hospital Affiliated to Hunan Normal University, Changsha, China
⨯
Yu Gan,

Roles Data curation, Investigation

Affiliation Physician of general surgery, Hunan Aerospace Hospital Affiliated to Hunan Normal University, Changsha, China
⨯
Liangliang Mi

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: 18874042262@163.com

Affiliation Physician of general surgery, Hunan Aerospace Hospital Affiliated to Hunan Normal University, Changsha, China

https://orcid.org/0009-0000-9067-1374

⨯

TBX20 promotes doxorubicin resistance in breast cancer cells through enhanced ABCC1 expression and inhibition of mitophagy

Shuai Nie,
Dejian Liu,
Jun Hu,
Yu Gan,
Liangliang Mi

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Published: July 17, 2026
https://doi.org/10.1371/journal.pone.0353376

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Breast cancer
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Cancer treatment
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Mitochondria
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Small interfering RNA
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Gene expression
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Protein expression
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Transfection
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Luciferase
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