The quantitative proteomics analysis of multi-stage gastric mucosal lesions associated with Helicobacter pylori infection

Xiaoxi Huang; Jiamei Ma; Yening Xiao; Jing Pan; Qin Xu; Xifan Cao; Yongchao Liu; Xiang Yi; Fang Tian

doi:10.1371/journal.pone.0353347

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Open Access

Peer-reviewed

Research Article

The quantitative proteomics analysis of multi-stage gastric mucosal lesions associated with Helicobacter pylori infection

Xiaoxi Huang ,

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: grrx7480@163.com

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China

https://orcid.org/0000-0002-1548-2335

⨯
Jiamei Ma,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Writing – original draft

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China

https://orcid.org/0000-0001-9672-9418

⨯
Yening Xiao,

Roles Investigation, Methodology, Project administration, Resources, Software

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Jing Pan,

Roles Data curation, Formal analysis, Software, Visualization, Writing – original draft

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Qin Xu,

Roles Investigation, Methodology, Software, Validation, Visualization

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Xifan Cao,

Roles Data curation, Validation

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Yongchao Liu,

Roles Methodology, Software

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Xiang Yi,

Roles Resources, Validation

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯
Fang Tian

Roles Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – review & editing

Affiliation The First Affiliated Hospital of Hainan University, Haikou People’s Hospital, Haikou, Hainan, China
⨯

The quantitative proteomics analysis of multi-stage gastric mucosal lesions associated with Helicobacter pylori infection

Xiaoxi Huang,
Jiamei Ma,
Yening Xiao,
Jing Pan,
Qin Xu,
Xifan Cao,
Yongchao Liu,
Xiang Yi,
Fang Tian

Published: July 31, 2026
https://doi.org/10.1371/journal.pone.0353347

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Gastritis
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Gastric cancer
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Proteomics
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Gastrointestinal tract
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Protein expression
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Oxidative phosphorylation
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Gastrointestinal infections
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Protein interaction networks
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