Chronic CBD treatment differentially modulates neurobehavioral outcomes and endocannabinoid signaling in an aged HIV-1 Tat transgenic mouse model

• Barkha J. Yadav-Samudrala ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: barkhaj@email.unc.edu

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0002-2967-2017

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• Morgan L. Johnson,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Ashima Ale,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Katherine Xiaofan Jiang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• William W. Y. Lee,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Amy Nguyen,

  Roles Data curation, Investigation, Visualization, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Dorian Ho,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Essie B. Acquah,

  Roles Formal analysis, Investigation, Software, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0009-0002-4598-0594

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• Isabella C. Orsucci,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Laith E. Sawaqed,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Gabriella Boyer,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Justin L. Poklis,

  Roles Data curation, Funding acquisition, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Wei Jiang,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Validation, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America, Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

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• Sylvia Fitting

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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