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Open Access

Peer-reviewed

Research Article

FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang ,

Contributed equally to this work with: Yan Wang, Xiaolong Xu

Roles Conceptualization

Affiliation Department of Endocrinology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China
⨯
Xiaolong Xu ,

Contributed equally to this work with: Yan Wang, Xiaolong Xu

Roles Formal analysis

Affiliation Department of Gastroenterology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China
⨯
Guanjun Huang,

Roles Funding acquisition, Software

Affiliation Department of Endocrinology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China
⨯
Hongyan Zhu,

Roles Validation, Writing – original draft

Affiliation Department of Endocrinology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China
⨯
Xuan Li,

Roles Software, Supervision

Affiliation Department of Endocrinology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China
⨯
Jue Lin

Roles Resources, Software, Writing – review & editing

* E-mail: 18034189@qq.com

Affiliation Department of Endocrinology, Shangrao Hospital affiliated to Nanchang University, Shangrao, Jiangxi, China

https://orcid.org/0009-0002-0916-1495

⨯

FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang,
Xiaolong Xu,
Guanjun Huang,
Hongyan Zhu,
Xuan Li,
Jue Lin

x

Published: August 4, 2026
https://doi.org/10.1371/journal.pone.0353264

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Medical risk factors
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Immune receptor signaling
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