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Open Access

Peer-reviewed

Research Article

Dysregulated glucocorticoid-responsive immune genes in peripheral blood mononuclear cells as a shared molecular signature of autism spectrum disorder and irritable bowel syndrome

Kuo Zhang ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

* E-mail: k18633550908@163.com

Affiliation Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China

https://orcid.org/0009-0001-7427-8748

⨯
Fangfang Mou,

Roles Conceptualization, Resources

Affiliation Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China
⨯
Jing Liu,

Roles Methodology, Resources

Affiliation Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China
⨯
Jianzhong Wang

Roles Resources, Validation, Writing – review & editing

Affiliation Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China
⨯

Dysregulated glucocorticoid-responsive immune genes in peripheral blood mononuclear cells as a shared molecular signature of autism spectrum disorder and irritable bowel syndrome

Kuo Zhang,
Fangfang Mou,
Jing Liu,
Jianzhong Wang

x

Published: July 9, 2026
https://doi.org/10.1371/journal.pone.0353181

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Gene expression
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Transcriptome analysis
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Immune cells
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Stress signaling cascade
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Transcriptional control
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