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Open Access
Peer-reviewed
Research Article
Artificial intelligence-detected HER2 strong-positive tumor proportion predicts FISH positivity and treatment response in breast cancer
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Seung Geun Song ,
Contributed equally to this work with: Seung Geun Song, Soo Ick Cho
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea
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Soo Ick Cho ,
Contributed equally to this work with: Seung Geun Song, Soo Ick Cho
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Lunit, Seoul, Republic of Korea
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Taeyong Sim,
Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Lunit, Seoul, Republic of Korea
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Sangwon Shin,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Lunit, Seoul, Republic of Korea
⨯ - Wonkyung Jung,
- Jisoo Shin,
- Sukjun Kim,
- Heon Song,
- Sérgio Pereira,
- Donggeun Yoo,
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Sun Kyung Baek,
Roles Data curation, Writing – review & editing
Affiliation Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Republic of Korea
⨯ -
Kiyong Na,
Roles Data curation, Writing – review & editing
Affiliation Department of Pathology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Republic of Korea
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Minsun Jung ,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
* E-mail: jjunglammy@yuhs.ac (MJ); swkdek@gmail.com (S-WK)
¶‡ These authors also contributed equally to this work.
Affiliation Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea
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So-Woon Kim
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
* E-mail: jjunglammy@yuhs.ac (MJ); swkdek@gmail.com (S-WK)
¶‡ These authors also contributed equally to this work.
Affiliation Department of Pathology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Republic of Korea
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Artificial intelligence-detected HER2 strong-positive tumor proportion predicts FISH positivity and treatment response in breast cancer
- Seung Geun Song,
- Soo Ick Cho,
- Taeyong Sim,
- Sangwon Shin,
- Wonkyung Jung,
- Jisoo Shin,
- Sukjun Kim,
- Heon Song,
- Sérgio Pereira,
- Donggeun Yoo
- Published: July 6, 2026
- https://doi.org/10.1371/journal.pone.0352979