The impact of pectin supplementation on systemic inflammation pathways, gut microbiome, and metabolic health in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A study protocol for a randomised controlled trial

• Noor Kifah Al-Tameemi ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

  * E-mail: noorkifahabdulhussein.al-tameemi@nottingham.ac.uk

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-5712-5889

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• Jane I. Grove,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

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• Caroline L. Hoad,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – review & editing

  Affiliations National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

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• Jessica Wong Sun Wai,

  Roles Project administration, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

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• Adina Olaru,

  Roles Project administration, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

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• Saikat Mandal,

  Roles Project administration, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0003-1250-5295

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• Katie E. Rollins,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation School of Medicine, University of Nottingham, Nottingham, United Kingdom

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• Christopher R. Bradley,

  Roles Formal analysis, Investigation, Methodology, Project administration, Software, Writing – review & editing

  Affiliations National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-2174-2279

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• Susan T. Francis,

  Roles Formal analysis, Investigation, Methodology, Project administration, Software, Writing – review & editing

  Affiliations National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

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• Penny A. Gowland,

  Roles Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliations National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

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• Ana M. Valdes,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

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• Guruprasad P. Aithal

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Writing – review & editing

  Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

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