A multimodal ConvNeXt-Tiny deep learning model for simultaneous prediction of IDH mutation and Ki-67 expression in gliomas

Juan Du; Linsha Yang; Duo Zhang; Jinguo Wang; Shuo Wu; Defeng Liu; Huiling Yi; Xin Liang; Xiaohan Wang; Qinglei Shi; Tao Zheng

doi:10.1371/journal.pone.0351757

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Open Access

Peer-reviewed

Research Article

A multimodal ConvNeXt-Tiny deep learning model for simultaneous prediction of IDH mutation and Ki-67 expression in gliomas

Juan Du,

Roles Writing – original draft

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Linsha Yang,

Roles Data curation

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Duo Zhang,

Roles Resources

Affiliation Department of Medical Imaging, Baoding No. 1 Central Hospital, Baoding, Hebei Province, P.R. China
⨯
Jinguo Wang,

Roles Data curation

Affiliation Department of Magnetic Resonance Imaging, Qinglong Manchu Autonomous County Traditional Chinese Medicine Hospital, Qinglong County, Qinhuangdao, Hebei Province, China
⨯
Shuo Wu,

Roles Resources

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Defeng Liu,

Roles Methodology

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Huiling Yi,

Roles Resources

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Xin Liang,

Roles Supervision

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Xiaohan Wang,

Roles Funding acquisition

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China
⨯
Qinglei Shi,

Roles Software

Affiliation Scientific Clinical Specialist, Siemens Healthineers China, Beijing, China
⨯
Tao Zheng

Roles Writing – review & editing

* E-mail: 357813707@qq.com

Affiliation Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, China

https://orcid.org/0000-0002-4845-1295

⨯

A multimodal ConvNeXt-Tiny deep learning model for simultaneous prediction of IDH mutation and Ki-67 expression in gliomas

Juan Du,
Linsha Yang,
Duo Zhang,
Jinguo Wang,
Shuo Wu,
Defeng Liu,
Huiling Yi,
Xin Liang,
Xiaohan Wang,
Qinglei Shi

Published: June 26, 2026
https://doi.org/10.1371/journal.pone.0351757

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Magnetic resonance imaging
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Deep learning
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Glioma
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