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Open Access
Peer-reviewed
Research Article
Impact of long-term cryopreservation on serum proteome and metallome: Implications for Biobank quality control
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Meng Lu ,
Contributed equally to this work with: Meng Lu, Xiongshun Liang
Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China
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Xiongshun Liang ,
Contributed equally to this work with: Meng Lu, Xiongshun Liang
Roles Data curation, Resources, Software, Writing – original draft, Writing – review & editing
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China, Shenzhen Center for Chronic Disease Control Biobank, Shenzhen, China
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Wanna Xu ,
Roles Data curation, Software, Supervision
¶‡ These authors also contributed equally to this work.
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China, Shenzhen Center for Chronic Disease Control Biobank, Shenzhen, China
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Hongxing Tan,
Roles Data curation, Methodology, Software
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China
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Junan Yan,
Roles Data curation, Methodology, Software
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China
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Xuqiao Hu ,
Roles Conceptualization, Funding acquisition, Methodology, Software, Writing – original draft, Writing – review & editing
* E-mail: haniahu@hotmail.com (XH); szbloodcenter@hotmail.com (WH)
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China
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Wenxu Hong
Roles Conceptualization, Data curation, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing
* E-mail: haniahu@hotmail.com (XH); szbloodcenter@hotmail.com (WH)
¶‡ These authors also contributed equally to this work.
Affiliations Shenzhen Center for Chronic Disease Control (Shenzhen Dermatology Hospital), Shenzhen, China, Shenzhen Institute of Dermatology, Shenzhen, China, Shenzhen Center for Chronic Disease Control Biobank, Shenzhen, China
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Impact of long-term cryopreservation on serum proteome and metallome: Implications for Biobank quality control
- Meng Lu,
- Xiongshun Liang,
- Wanna Xu,
- Hongxing Tan,
- Junan Yan,
- Xuqiao Hu,
- Wenxu Hong
- Published: June 25, 2026
- https://doi.org/10.1371/journal.pone.0351736