A multicenter, randomized, parallel-group confirmatory study protocol to evaluate the efficacy of Soft Protector CPC, a novel oral mucosal protectant, in preventing oral mucositis and alleviating pain in patients with breast cancer

• Kazuhiro Omori ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: kazu@okayama-u.ac.jp

  Affiliation Department of Pathophysiology-Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

  https://orcid.org/0000-0002-4129-1401

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• Kohei Furukawa,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Dentistry and Oral Surgery, Shikoku Cancer Center, Ehime, Japan

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• Masatoshi Usubuchi,

  Roles Investigation, Methodology, Writing – review & editing

  Current Address: Department of Dentistry and Oral Surgery, Hakodate Medical Center, Hokkaido, Japan

  Affiliation Department of Dentistry, Miyagi Cancer Center, Miyagi, Japan

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• Tomofumi Hamada,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Dentistry and Oral Surgery, Sagara Hospital, Kagoshima, Japan

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• Tadahiko Shien,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Breast and Endocrine Surgery, Okayama University Hospital, Okayama, Japan

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• Michihiro Yoshida,

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan

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• Yuki Nakatsuka,

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan

  https://orcid.org/0009-0007-2054-7483

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• Katsuyuki Hotta,

  Roles Supervision, Writing – review & editing

  Affiliation Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan

  https://orcid.org/0000-0002-0112-0843

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• Soichiro Ibaragi,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

  https://orcid.org/0000-0003-2897-1231

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• Shogo Takashiba

  Roles Supervision, Writing – review & editing

  Affiliation Department of Pathophysiology-Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

  https://orcid.org/0000-0002-4712-6829

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