Development of an exploratory prediction model for preoperative CK19 expression in esophageal cancer driven by radiomics and machine learning

Jiafu Yang; Sicheng Wang; Xin Chen; Liping Liu; Yangkang Li

doi:10.1371/journal.pone.0350744

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Open Access

Peer-reviewed

Research Article

Development of an exploratory prediction model for preoperative CK19 expression in esophageal cancer driven by radiomics and machine learning

Jiafu Yang,

Roles Conceptualization, Supervision, Writing – original draft

Affiliation Department of Radiology, Guangdong Engineering Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics(Proposed)/GuangDong Engineering Technology Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics, Cancer Hospital of Shantou University Medical College, Shantou, China

https://orcid.org/0009-0004-2036-2989

⨯
Sicheng Wang,

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

Affiliation University of Macau, Macau, China
⨯
Xin Chen,

Roles Formal analysis, Writing – original draft

Affiliation University of Macau, Macau, China
⨯
Liping Liu,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Radiology, Guangdong Engineering Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics(Proposed)/GuangDong Engineering Technology Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics, Cancer Hospital of Shantou University Medical College, Shantou, China
⨯
Yangkang Li

Roles Methodology, Writing – review & editing

* E-mail: liyangkang035@163.com

Affiliation Department of Radiology, Guangdong Engineering Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics(Proposed)/GuangDong Engineering Technology Research Center of AI-Powered Precision Cancer Diagnostics and Therapeutics, Cancer Hospital of Shantou University Medical College, Shantou, China

https://orcid.org/0000-0002-0860-519X

⨯

Development of an exploratory prediction model for preoperative CK19 expression in esophageal cancer driven by radiomics and machine learning

Jiafu Yang,
Sicheng Wang,
Xin Chen,
Liping Liu,
Yangkang Li

Published: June 1, 2026
https://doi.org/10.1371/journal.pone.0350744

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Machine learning
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Computed axial tomography
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