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Open Access
Peer-reviewed
Research Article
Adverse effects of removable orthodontic aligners: A systematic review with single-arm meta-analysis
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Cintia Ronchi Lemos ,
Contributed equally to this work with: Cintia Ronchi Lemos, Marianella Aguilar Ventura Fadel
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil
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Marianella Aguilar Ventura Fadel ,
Contributed equally to this work with: Cintia Ronchi Lemos, Marianella Aguilar Ventura Fadel
Roles Data curation, Investigation, Validation, Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil
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Helena Polmann ,
Roles Methodology, Supervision, Validation, Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil
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Júlia Meller Dias de Oliveira ,
Roles Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil
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Patrícia Pauletto ,
Roles Conceptualization, Methodology, Supervision, Writing – review & editing
* E-mail: patricia.pauletto@udla.edu.ec
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation School of Dentistry, Universidad De Las Américas (UDLA), Quito, Ecuador
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Cristine Miron Stefani ,
Roles Methodology, Validation, Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Brazilian Center for Evidence-Based Research (COBE), University of Brasilia, Brasilia, Brazil
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Carlos Flores-Mir ,
Roles Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliation Mike Petryk School of Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Graziela De Luca Canto
Roles Conceptualization, Formal analysis, Methodology, Validation, Writing – review & editing
¶‡ CRL, MAVF, HP, JMDO, PP, CMS, CF-M, and GDLC also contributed equally to this work.
Affiliations Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil, Postgraduate Program in Evidence-Based Health, Federal University of São Paulo, São Paulo, Brazil
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Adverse effects of removable orthodontic aligners: A systematic review with single-arm meta-analysis
- Cintia Ronchi Lemos,
- Marianella Aguilar Ventura Fadel,
- Helena Polmann,
- Júlia Meller Dias de Oliveira,
- Patrícia Pauletto,
- Cristine Miron Stefani,
- Carlos Flores-Mir,
- Graziela De Luca Canto
- Published: July 20, 2026
- https://doi.org/10.1371/journal.pone.0350741