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Open Access
Peer-reviewed
Research Article
Tear-film imaging measurements of the lipid and muco-aqueous layers and their association with dry eye disease signs and symptoms in adults: A pilot, prospective, cross-sectional study at a tertiary eye care center
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Isaac M. Tessone,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Ophthalmology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America
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Richard B. Rosen,
Roles Investigation, Methodology, Supervision
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Hernan Rios,
Roles Formal analysis
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Masako Chen,
Roles Investigation, Supervision
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Alice Chandra Verticchio Vercellin,
Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing
Affiliation Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Brent A. Siesky,
Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Paul A. Sidoti,
Roles Investigation, Methodology, Supervision
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Kira Manusis,
Roles Investigation, Supervision
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Anna Fabczak-Kubicka,
Roles Investigation, Methodology
Affiliation Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Keren Wood Shalem,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliations Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America, Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Gal Antman
Roles Conceptualization, Investigation, Methodology, Project administration, Writing – original draft
* E-mail: antmangal@gmail.com
Affiliations Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Ophthalmology, Rabin Medical Center, Petah Tikwa, Central, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Tear-film imaging measurements of the lipid and muco-aqueous layers and their association with dry eye disease signs and symptoms in adults: A pilot, prospective, cross-sectional study at a tertiary eye care center
- Isaac M. Tessone,
- Richard B. Rosen,
- Hernan Rios,
- Masako Chen,
- Alice Chandra Verticchio Vercellin,
- Brent A. Siesky,
- Paul A. Sidoti,
- Kira Manusis,
- Anna Fabczak-Kubicka,
- Keren Wood Shalem
- Published: July 10, 2026
- https://doi.org/10.1371/journal.pone.0350397