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Open Access
Study Protocol
Effects of taurine supplementation on metabolic health and biological aging in healthcare workers: A protocol for a triple-blinded, Bayesian-optimized phase II randomized controlled trial
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Mandy H. M. Chu,
Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Jacky K. M. Lai,
Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Anna Lee,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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William K. K. Wu,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Ziheng Huang,
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Henry M. K. Wong,
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Laptin Ho,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Hao Su,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Samantha S. M. Ho,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Xinbo Xu,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Warren Pavey,
Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing
Affiliation Institute of Heart and Lung Research Institute, Perth, Western Australia, Australia
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David J. R. Morgan,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliations Institute of Heart and Lung Research Institute, Perth, Western Australia, Australia, Department of Intensive Care Medicine, Fiona Stanley Hospital, Perth, Western Australia, Australia
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Matthew T. V. Chan,
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Kwok M. Ho
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
* E-mail: kmho@cuhk.edu.hk
Affiliation Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong SAR, China
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Effects of taurine supplementation on metabolic health and biological aging in healthcare workers: A protocol for a triple-blinded, Bayesian-optimized phase II randomized controlled trial
- Mandy H. M. Chu,
- Jacky K. M. Lai,
- Anna Lee,
- William K. K. Wu,
- Ziheng Huang,
- Henry M. K. Wong,
- Laptin Ho,
- Hao Su,
- Samantha S. M. Ho,
- Xinbo Xu
- Published: May 27, 2026
- https://doi.org/10.1371/journal.pone.0350389