Data subdivision approach enhances machine learning-based mortality prediction in pediatric ICU patients

Wenqian Chen; Benjamin Lee; Zexi Zang; Junfeng Li; Lingna Huang; Hang Xing; Yanli Ren

doi:10.1371/journal.pone.0349772

Loading metrics

Open Access

Peer-reviewed

Research Article

Data subdivision approach enhances machine learning-based mortality prediction in pediatric ICU patients

Wenqian Chen ,

Contributed equally to this work with: Wenqian Chen, Benjamin Lee

Roles Data curation, Formal analysis, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Neonatology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China
⨯
Benjamin Lee ,

Contributed equally to this work with: Wenqian Chen, Benjamin Lee

Roles Data curation, Formal analysis, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Pediatrics, Women & Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

https://orcid.org/0009-0007-6982-607X

⨯
Zexi Zang,

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Department of Pediatrics, Women & Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Junfeng Li,

Roles Formal analysis, Writing – review & editing

Affiliation Henan Key Laboratory of Fertility Protection and Aristogenesis, Department of Reproductive Center, Luohe Central Hospital, Luohe, Henan, China
⨯
Lingna Huang,

Roles Formal analysis, Writing – review & editing

Affiliation Department of Gynecology and Obstetrics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China
⨯
Hang Xing ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: hang_xing@brown.edu (HX); rylwheat@126.com (YR)

Affiliation Department of Pediatrics, Women & Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Yanli Ren

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: hang_xing@brown.edu (HX); rylwheat@126.com (YR)

Affiliation Department of Neonatology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China
⨯

Data subdivision approach enhances machine learning-based mortality prediction in pediatric ICU patients

Wenqian Chen,
Benjamin Lee,
Zexi Zang,
Junfeng Li,
Lingna Huang,
Hang Xing,
Yanli Ren

Published: June 16, 2026
https://doi.org/10.1371/journal.pone.0349772

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Machine learning
Is the Subject Area "Machine learning" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Trees
Is the Subject Area "Trees" applicable to this article?

Thanks for your feedback.
Pediatrics
Is the Subject Area "Pediatrics" applicable to this article?

Thanks for your feedback.
Forecasting
Is the Subject Area "Forecasting" applicable to this article?

Thanks for your feedback.
Sepsis
Is the Subject Area "Sepsis" applicable to this article?

Thanks for your feedback.
Electrolytes
Is the Subject Area "Electrolytes" applicable to this article?

Thanks for your feedback.
Pediatric infections
Is the Subject Area "Pediatric infections" applicable to this article?

Thanks for your feedback.