Estimating HIV incidence and assessing associated risk factors among adults: Evidence from the 2018–2022 HIV vaccine preparedness cohort in Masaka, Uganda

Sylvia Kusemererwa; Sheila Kansiime; Gertrude Mutonyi; Ayoub Kakande; Shamim Nabukenya; Aeron Namirembe; Naphtal Erima; Doreen Joan Asio; Elizabeth Mbabazi Atuhura; Shamim Ssendagire; Martin Onyango; Julie Fox; Sheena McCormack; Pontiano Kaleebu; Eugene Ruzagira; on behalf of the PrEPVacc Study Team

doi:10.1371/journal.pone.0348769

Loading metrics

Open Access

Peer-reviewed

Research Article

Estimating HIV incidence and assessing associated risk factors among adults: Evidence from the 2018–2022 HIV vaccine preparedness cohort in Masaka, Uganda

Sylvia Kusemererwa ,

Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sylvia.kusemererwa@mrcuganda.org, kansykarus@gmail.com

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda

https://orcid.org/0000-0002-1390-109X

⨯
Sheila Kansiime,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Gertrude Mutonyi,

Roles Conceptualization, Data curation, Methodology, Software, Validation, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Ayoub Kakande,

Roles Conceptualization, Data curation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Shamim Nabukenya,

Roles Data curation, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Aeron Namirembe,

Roles Data curation, Methodology, Software, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Naphtal Erima,

Roles Data curation, Methodology, Software, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Doreen Joan Asio,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Elizabeth Mbabazi Atuhura,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Shamim Ssendagire,

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Martin Onyango,

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda
⨯
Julie Fox,

Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliation King’s College London, London, United Kingdom
⨯
Sheena McCormack,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom
⨯
Pontiano Kaleebu,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Eugene Ruzagira,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
[ ... ],
on behalf of the PrEPVacc Study Team

¶PrEPVacc Study Team is provided in the Acknowledgments.
⨯
[ view all ]
[ view less ]

Estimating HIV incidence and assessing associated risk factors among adults: Evidence from the 2018–2022 HIV vaccine preparedness cohort in Masaka, Uganda

Sylvia Kusemererwa,
Sheila Kansiime,
Gertrude Mutonyi,
Ayoub Kakande,
Shamim Nabukenya,
Aeron Namirembe,
Naphtal Erima,
Doreen Joan Asio,
Elizabeth Mbabazi Atuhura,
Shamim Ssendagire

Published: May 8, 2026
https://doi.org/10.1371/journal.pone.0348769

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
HIV epidemiology
Is the Subject Area "HIV epidemiology" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
HIV prevention
Is the Subject Area "HIV prevention" applicable to this article?

Thanks for your feedback.
Virus testing
Is the Subject Area "Virus testing" applicable to this article?

Thanks for your feedback.
HIV diagnosis and management
Is the Subject Area "HIV diagnosis and management" applicable to this article?

Thanks for your feedback.
HIV vaccines
Is the Subject Area "HIV vaccines" applicable to this article?

Thanks for your feedback.
Preventive medicine
Is the Subject Area "Preventive medicine" applicable to this article?

Thanks for your feedback.