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Open Access
Peer-reviewed
Research Article
Effects of nebulized dexmedetomidine for premedication on the parameters of oxidative and inflammatory stress in children undergoing tonsillotomy and adenoidectomy: A pilot randomized controlled trial
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Vesna V. Stevanovic ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Conceptualization, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
* E-mail: nadjenka9@gmail.com
Affiliations Department of Anesthesiology, Mother and Child Health Care Institute of Serbia “Dr Vukan Cupic”, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Ana D. Mandras ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Investigation, Methodology, Writing – original draft
Affiliations Department of Anesthesiology, Mother and Child Health Care Institute of Serbia “Dr Vukan Cupic”, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Ana A. Djuric ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department for Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
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Ivan A. Soldatovic ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Formal analysis, Writing – review & editing
Affiliations Institute of Medical Biostatistics, Faculty of Medicine, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Dragana V. Bojanin ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Investigation, Writing – review & editing
Affiliation Department for Clinical Chemistry and Hematology, Mother and Child Health Care Institute of Serbia “Dr Vukan Cupic”, Belgrade, Serbia
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Branko Lj. Lukic ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Writing – review & editing
Affiliation Department of general surgery, Clinical Hospital Center “Zemun”, Belgrade, Serbia
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Predrag D. Stevanovic ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Methodology, Supervision, Writing – review & editing
Affiliations Department of Anesthesiology, Clinical Hospital Center “Dr Dragisa Misovic-Dedinje”, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Marija M. Stevic ,
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Validation
Affiliations Department of Anesthesiology, University Children’s Hospital, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Aleksandar M. Vlahovic
Contributed equally to this work with: Vesna V. Stevanovic, Ana D. Mandras, Ana A. Djuric, Ivan A. Soldatovic, Dragana V. Bojanin, Branko Lj. Lukic, Predrag D. Stevanovic, Marija M. Stevic, Aleksandar M. Vlahovic
Roles Validation
Affiliations Department of Plastic Surgery, Mother and Child Health Care Institute of Serbia “Dr Vukan Cupic”, Belgrade, Serbia, University of Belgrade, Faculty of Medicine, Belgrade, Serbia
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Effects of nebulized dexmedetomidine for premedication on the parameters of oxidative and inflammatory stress in children undergoing tonsillotomy and adenoidectomy: A pilot randomized controlled trial
- Vesna V. Stevanovic,
- Ana D. Mandras,
- Ana A. Djuric,
- Ivan A. Soldatovic,
- Dragana V. Bojanin,
- Branko Lj. Lukic,
- Predrag D. Stevanovic,
- Marija M. Stevic,
- Aleksandar M. Vlahovic
- Published: May 11, 2026
- https://doi.org/10.1371/journal.pone.0348763