High-yield recombinant production of the semaglutide main chain P29 intermediate using SNAC-tagged enterokinase-cleavable fusion peptides

• Qingyu Qi ,

  Contributed equally to this work with: Qingyu Qi, Ge Gao

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Laboratory Technology, School of Medicine, Xi’An Pei Hua University, Xi’an, Shaanxi, China, Shaanxi Proandy Biotechnology Development Company, Xi’an, Shaanxi, China

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• Ge Gao ,

  Contributed equally to this work with: Qingyu Qi, Ge Gao

  Roles Conceptualization, Data curation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

  Affiliations Department of Medical Laboratory Technology, School of Medicine, Xi’An Pei Hua University, Xi’an, Shaanxi, China, Shaanxi Proandy Biotechnology Development Company, Xi’an, Shaanxi, China

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• Guodong Li ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: tonghie@163.com (LG); b.x.ling@nus.edu.sg (BX)

  Affiliation Shaanxi Proandy Biotechnology Development Company, Xi’an, Shaanxi, China

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• Xianling Bian

  Roles Conceptualization, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tonghie@163.com (LG); b.x.ling@nus.edu.sg (BX)

  Affiliation Department of Biochemistry, Infectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

  https://orcid.org/0009-0008-0911-6911

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