Transcriptomic study of WSSV infection in Litopenaeus vannamei lymphoid organ via single nuclei RNA sequencing

Alexandra Florea; Nick Wade; Sarah J. Salisbury; James Furniss; Clémence Fraslin; Ambre Chapuis; Kallen Sullivan; Robert Stewart; Diego Robledo; Tim P. Bean

doi:10.1371/journal.pone.0348006

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Open Access

Peer-reviewed

Research Article

Transcriptomic study of WSSV infection in Litopenaeus vannamei lymphoid organ via single nuclei RNA sequencing

Alexandra Florea ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: alexandra.florea@ed.ac.uk

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

https://orcid.org/0009-0008-6393-9177

⨯
Nick Wade,

Roles Investigation

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom
⨯
Sarah J. Salisbury,

Roles Investigation, Methodology, Writing – review & editing

Affiliations The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom, University of Exeter, Exeter, United Kingdom
⨯
James Furniss,

Roles Investigation

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

https://orcid.org/0000-0001-5643-2070

⨯
Clémence Fraslin,

Roles Investigation, Writing – review & editing

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom
⨯
Ambre Chapuis,

Roles Investigation

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

https://orcid.org/0000-0002-2915-6864

⨯
Kallen Sullivan,

Roles Investigation

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

https://orcid.org/0009-0007-0396-7873

⨯
Robert Stewart,

Roles Investigation

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom
⨯
Diego Robledo,

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliations The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom, University of Santiago de Compostela, Santiago de Compostela, Spain
⨯
Tim P. Bean

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

https://orcid.org/0000-0002-2544-9918

⨯

Transcriptomic study of WSSV infection in Litopenaeus vannamei lymphoid organ via single nuclei RNA sequencing

Alexandra Florea,
Nick Wade,
Sarah J. Salisbury,
James Furniss,
Clémence Fraslin,
Ambre Chapuis,
Kallen Sullivan,
Robert Stewart,
Diego Robledo,
Tim P. Bean

Published: April 27, 2026
https://doi.org/10.1371/journal.pone.0348006

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