A single dose of purified human antibody from transchromosomic bovines mitigates aerosolized Venezuelan equine encephalitis virus disease in cynomolgus macaques

• Chengqun Sun,

  Roles Formal analysis, Investigation, Visualization

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Christina Gardner,

  Roles Formal analysis, Investigation, Resources, Visualization, Writing – review & editing

  Affiliation Current address: United States Army Research Institute of Infectious Disease, Virology Division, Frederick, Maryland, United States of America

  ⨯
• Long Kwan Metthew Lam,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9700-4988

  ⨯
• Jeneveve Lundy,

  Roles Investigation

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Katherine O’Malley,

  Roles Investigation, Visualization

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Thomas Luke,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Current address: United States Army Research Institute of Infectious Disease, Virology Division, Frederick, Maryland, United States of America

  ⨯
• Kanakatte Raviprakash,

  Roles Resources

  Affiliation Naval Medical Research Center Department of Viral and Rickettsial Diseases, Silver Spring, Maryland, United States of America

  ⨯
• Amy L. Hartman,

  Roles Investigation, Methodology

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Graduate School of Public Health, Department of Infectious Diseases and Microbiology, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Nicholas A. Crossland,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliations National Emerging Infectious Diseases Laboratories, Comparative Pathology Laboratory, Boston University, Boston, Massachusetts, United States of America, Boston University Chobanian and Avedisian School of Medicine, Department of Pathology and Laboratory Medicine, Boston, Massachusetts, United States of America

  ⨯
• Hua Wu,

  Roles Resources

  Affiliation S.A.B. Biotherapeutics, Inc, Miami, Florida, United States of America

  ⨯
• Jin-an Jiao,

  Roles Resources

  Affiliation S.A.B. Biotherapeutics, Inc, Miami, Florida, United States of America

  ⨯
• Christoph Bausch,

  Roles Resources

  Affiliation S.A.B. Biotherapeutics, Inc, Miami, Florida, United States of America

  ⨯
• Eddie Sullivan,

  Roles Resources

  Affiliation S.A.B. Biotherapeutics, Inc, Miami, Florida, United States of America

  ⨯
• Douglas S. Reed,

  Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – review & editing

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  ⨯
• William B. Klimstra

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: klimstra@pitt.edu

  Affiliations University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh School of Medicine, Department of Immunology, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0003-4506-7842

  ⨯