Single-cell multiomics data analysis of potential receptors and therapeutic drugs for epilepsy patients comorbid with depression

Guiqin Bai; Xuerong Zhou; Cheng Xiong; Xi Kang; Ruiqi Huang; Dazhang Bai; Peilin Zhao; Tao Peng; Cheer Muer; Guohui Jiang; Shushan Zhang

doi:10.1371/journal.pone.0347526

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Open Access

Peer-reviewed

Research Article

Single-cell multiomics data analysis of potential receptors and therapeutic drugs for epilepsy patients comorbid with depression

Guiqin Bai ,

Contributed equally to this work with: Guiqin Bai, Xuerong Zhou

Roles Formal analysis, Funding acquisition, Writing – review & editing

Affiliation Department of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan, China

https://orcid.org/0000-0001-8815-3113

⨯
Xuerong Zhou ,

Contributed equally to this work with: Guiqin Bai, Xuerong Zhou

Roles Formal analysis, Project administration, Writing – original draft

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Cheng Xiong,

Roles Methodology

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Xi Kang,

Roles Validation

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Ruiqi Huang,

Roles Validation

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Dazhang Bai,

Roles Funding acquisition, Investigation

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Peilin Zhao,

Roles Investigation

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Tao Peng,

Roles Investigation

Affiliation Department of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Cheer Muer,

Roles Investigation

Affiliation Department of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Guohui Jiang,

Roles Conceptualization

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯
Shushan Zhang

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

^* susan448@163.com

Affiliation Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurological Diseases, North Sichuan Medical College, Nanchong, Sichuan, China
⨯

Single-cell multiomics data analysis of potential receptors and therapeutic drugs for epilepsy patients comorbid with depression

Guiqin Bai,
Xuerong Zhou,
Cheng Xiong,
Xi Kang,
Ruiqi Huang,
Dazhang Bai,
Peilin Zhao,
Tao Peng,
Cheer Muer,
Guohui Jiang

Published: April 22, 2026
https://doi.org/10.1371/journal.pone.0347526

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