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Systemic iron availability differentially shapes tumor and brain iron handling in a sex-dependent manner in glioblastoma
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Emily Tufano,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Neurosurgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯ - Kondaiah Palsa,
- Rebecka O. Serpa,
- Timothy B. Helmuth,
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Gabriela Remit-Berthet,
Roles Resources, Writing – review & editing
Affiliation Department of Neurosurgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯ - Sara Mills-Huffnagle,
- Mathias Kant,
- Aurosman Sahu,
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James R. Connor
Roles Conceptualization, Funding acquisition, Methodology, Resources, Writing – original draft, Writing – review & editing
* E-mail: jconnor@pennstatehealth.psu.edu
Affiliations Department of Neurosurgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America, Department of Neuroscience and Experimental Therapeutics, The Pennsylvania State University College of Medicine, Hershey Pennsylvania, United States of America, Penn State Neuroscience Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
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https://orcid.org/0000-0002-9090-4403
Systemic iron availability differentially shapes tumor and brain iron handling in a sex-dependent manner in glioblastoma
- Emily Tufano,
- Kondaiah Palsa,
- Rebecka O. Serpa,
- Timothy B. Helmuth,
- Gabriela Remit-Berthet,
- Sara Mills-Huffnagle,
- Mathias Kant,
- Aurosman Sahu,
- James R. Connor
- Published: April 20, 2026
- https://doi.org/10.1371/journal.pone.0347520