EP300 promotes bladder cancer cell migration through SNAI2

Qing Zhang; Chongjie He; Yingzhou Hong; Tao Huang; Shuangsheng Deng; Cheng Peng; Haifeng Wang; Chunming Guo

doi:10.1371/journal.pone.0347209

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Open Access

Peer-reviewed

Research Article

EP300 promotes bladder cancer cell migration through SNAI2

Qing Zhang,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliations Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China, Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Chongjie He,

Roles Data curation, Methodology, Validation

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Yingzhou Hong,

Roles Data curation, Methodology, Software

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Tao Huang,

Roles Investigation

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Shuangsheng Deng,

Roles Project administration, Resources

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Cheng Peng,

Roles Resources, Software, Supervision

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Haifeng Wang,

Roles Resources, Supervision

Affiliation Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Chunming Guo

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: chunmingguo@ynu.edu.cn

Affiliation Yunnan Key Laboratory of Cell Metabolism and Disease, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China

https://orcid.org/0009-0007-6141-0037

⨯

EP300 promotes bladder cancer cell migration through SNAI2

Qing Zhang,
Chongjie He,
Yingzhou Hong,
Tao Huang,
Shuangsheng Deng,
Cheng Peng,
Haifeng Wang,
Chunming Guo

Published: June 8, 2026
https://doi.org/10.1371/journal.pone.0347209

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Bladder cancer
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Cancer treatment
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Cancer cell migration
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Bladder
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Carcinogenesis
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Histones
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Mouse models
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Prostate cancer
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