Evaluation of therapeutic efficacy of baloxavir marboxil against high pathogenicity avian influenza virus infection in duck model

• Yo Shimazu,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Norikazu Isoda,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, One Health Research Center, Hokkaido University, Sapporo, Hokkaido, Japan, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan, Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Hokkaido, Japan

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• Takahiro Hiono,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, One Health Research Center, Hokkaido University, Sapporo, Hokkaido, Japan, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan, Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Hokkaido, Japan

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• Yik Lim Hew,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Daiki Kobayashi,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

  https://orcid.org/0009-0007-0072-1042

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• Misato Shibazaki,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan

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• Bao Linh Nguyen,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Tatsuru Morita,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Ryo Daniel Obara,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan

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• Mariko Miki,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan

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• Hiromi Osaki,

  Roles Conceptualization, Methodology, Validation, Writing – review & editing

  Affiliation Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan

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• Takao Shishido,

  Roles Conceptualization, Methodology, Validation, Writing – review & editing

  Affiliation Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan

  https://orcid.org/0000-0002-2549-0945

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• Yoshinori Ikenaka,

  Roles Data curation, Formal analysis, Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliations One Health Research Center, Hokkaido University, Sapporo, Hokkaido, Japan, Laboratory of Toxicology, Department of Environmental Veterinary Science, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa

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• Yoshihiro Sakoda

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Validation, Writing – review & editing

  * E-mail: sakoda@vetmed.hokudai.ac.jp

  Affiliations Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, One Health Research Center, Hokkaido University, Sapporo, Hokkaido, Japan, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan, Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Hokkaido, Japan

  https://orcid.org/0000-0001-7021-1688

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