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Open Access

Peer-reviewed

Research Article

A cross-sectional study on the impact of early systematic antidepressant therapy on positive/negative affect and impulsivity in euthymic bipolar disorder patients

Dongyu Han ,

Roles Data curation, Writing – original draft

¶‡ The two authors share the first authorship on this work.

Affiliations Tianjin Mental Health Center, Tianjin Anding Hospital, Tianjin, China, Tianjin Medical University, Tianjin, China
⨯
Peng Cui ,

Roles Data curation, Writing – original draft

¶‡ The two authors share the first authorship on this work.

Affiliation Tianjin Mental Health Center, Tianjin Anding Hospital, Tianjin, China
⨯
Mingjin Wang,

Roles Formal analysis, Methodology

Affiliation Tianjin Medical University, Tianjin, China
⨯
Xiaofei Hou,

Roles Formal analysis, Methodology

Affiliation Tianjin Mental Health Center, Tianjin Anding Hospital, Tianjin, China
⨯
Chenghao Yang ,

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: yts83420@163.com (CY); jieli@tjmhc.com (JL)

Affiliation Tianjin Mental Health Center, Tianjin Anding Hospital, Tianjin, China

https://orcid.org/0000-0002-3424-6004

⨯
Jie Li

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: yts83420@163.com (CY); jieli@tjmhc.com (JL)

Affiliations Tianjin Mental Health Center, Tianjin Anding Hospital, Tianjin, China, Tianjin Medical University, Tianjin, China
⨯

A cross-sectional study on the impact of early systematic antidepressant therapy on positive/negative affect and impulsivity in euthymic bipolar disorder patients

Dongyu Han,
Peng Cui,
Mingjin Wang,
Xiaofei Hou,
Chenghao Yang,
Jie Li

x

Published: April 22, 2026
https://doi.org/10.1371/journal.pone.0346872

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Impulsivity
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Antidepressants
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Antidepressant drug therapy
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Bipolar disorder
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Depression
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Emotions
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Suicide
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Medical risk factors
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