Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system

Deye Ge; Liyan Wu; Jingrong Yang; Jingxian Sun; Jinying Wang; Jingxin Wang; Huihui Song; Ran Wei; Zecheng Xu; Binbin Zhao; Rongfei Sun; Yifei Wang

doi:10.1371/journal.pone.0346797

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Open Access

Peer-reviewed

Research Article

Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system

Deye Ge,

Roles Conceptualization, Writing – original draft, Writing – review & editing

Affiliation First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China
⨯
Liyan Wu,

Roles Data curation

Affiliation Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Jingrong Yang,

Roles Data curation

Affiliation First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China
⨯
Jingxian Sun,

Roles Software, Validation

Affiliation Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Jinying Wang,

Roles Methodology

Affiliation The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Jingxin Wang,

Roles Methodology

Affiliation Infection Prevention and Control (IPC) Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Huihui Song,

Roles Validation

Affiliation Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Ran Wei,

Roles Software

Affiliation Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Zecheng Xu,

Roles Visualization

Affiliation First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China
⨯
Binbin Zhao,

Roles Visualization

Affiliation Institute of Gerontology, Hubei University of Chinese Medicine, Wuhan, China
⨯
Rongfei Sun,

Roles Visualization

Affiliation Heart Center, Shandong Public Health Clinical Center, Jinan, China
⨯
Yifei Wang

Roles Writing – review & editing

* E-mail: 71000686@sdutcm.edu.cn

Affiliation Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China

https://orcid.org/0000-0003-0562-3058

⨯

Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system

Deye Ge,
Liyan Wu,
Jingrong Yang,
Jingxian Sun,
Jinying Wang,
Jingxin Wang,
Huihui Song,
Ran Wei,
Zecheng Xu,
Binbin Zhao

Published: April 13, 2026
https://doi.org/10.1371/journal.pone.0346797

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