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Open Access
Peer-reviewed
Research Article
Upregulation of CD1d and ULBP3 on B cells from healthy donors and chronic lymphocytic leukaemia patients does not prime them for killing by γδ T cells
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Julie David,
Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland, Department of Haematology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Amy Walsh,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Ke Sin Seow,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Ellen Walsh,
Roles Methodology, Resources, Writing – review & editing
Affiliations Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland, Department of Genitourinary Medicine and Infectious diseases, St. James’s Hospital, Dublin, Ireland
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Stefan Elekes,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Rohit Upadhyay,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Nawal A. B. Taher,
Roles Investigation, Methodology, Writing – review & editing
Current address: Pharmacology Department, School of Medicine, Gharian University, Gharyan City, Libya
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Samiha Al Siyabi,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Ashanty M. Melo,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Carmel Waldron,
Roles Investigation, Resources, Writing – review & editing
Affiliation Department of Haematology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Elisabeth Vandenberghe,
Roles Methodology, Resources, Writing – review & editing
Affiliation Department of Haematology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Anthony M. McElligott,
Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Writing – review & editing
Affiliation Department of Haematology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Derek G. Doherty
Roles Conceptualization, Data curation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: derek.doherty@tcd.ie
Affiliation Department of Immunology, School of Medicine, Trinity Translational Medicine Institute, St. James’s Hospital, Dublin, Ireland
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Upregulation of CD1d and ULBP3 on B cells from healthy donors and chronic lymphocytic leukaemia patients does not prime them for killing by γδ T cells
- Julie David,
- Amy Walsh,
- Ke Sin Seow,
- Ellen Walsh,
- Stefan Elekes,
- Rohit Upadhyay,
- Nawal A. B. Taher,
- Samiha Al Siyabi,
- Ashanty M. Melo,
- Carmel Waldron
- Published: April 20, 2026
- https://doi.org/10.1371/journal.pone.0346684